Indications and recommendations for use of the drug Advantan

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Dermatitis is a disease that is treated comprehensively with the use of antihistamines, hormonal, antifungal drugs, as well as antibiotics and immunomodulators. Oral medications eliminate the internal cause of inflammation, and combat its external manifestations - rash, redness and irritation of the skin - using hormonal, non-hormonal and combined ointments. Both patients and specialists have an ambiguous attitude towards external therapy products containing hormones, since such drugs, despite their effectiveness, quite often cause side effects. To be fair, it should be noted that most often this happens when using ointments without a doctor’s recommendation. However, in cases of acute contact allergic dermatitis or relapse of the disease, especially if there are signs of the development of eczema , neurodermatitis and in cases where the rash is caused by taking medications, only hormonal ointments , the list of which is quite wide, can quickly relieve inflammation and stop the development of dermatitis.

Advantages of hormonal ointments for dermatitis:

fast action (improvement after just one or two applications);

high efficiency (instant relief of itching, swelling and redness).

Disadvantages of hormonal ointments for dermatitis:

• slow healing of wounds and cuts, if they are present in the affected area;
• exacerbation of acne;
• cessation or, on the contrary, increase in hair growth in the area of ​​application of hormonal ointment;
• subcutaneous hemorrhages;
• formation of spider veins;
• hyperpigmentation of the skin and loss of elasticity, up to atrophy, that is, pathological thinning of the subcutaneous tissue (which is why hormonal ointments are not recommended for use on the skin of the face);
• The hormones contained in the ointment for dermatitis weaken the barrier function of the skin, as a result of which a bacterial or fungal infection develops in the affected area.

Attention! After prolonged use of ointments with hormones, withdrawal syndrome may occur when the skin condition sharply worsens, as soon as you stop using the product. Patients are afraid of this condition and often continue to use the drug, although this should not be done. To reduce possible risks, a few days before stopping the drug, reduce the dosage of the drug and start taking vitamin and mineral complexes , which will support the body after the hormones are stopped.

Ointment release form

Advantan is produced in two forms - with a fatty base and an aqueous one, which are prescribed for the same diseases. At the same time, the fatty preparation eliminates dry skin during long-term chronic conditions, and the water-emulsion composition of the product helps restore the water-fat balance of the skin.

Additional substances in fatty form:

• liquid and soft type of paraffin;
• microcrystalline composition of wax;
• enriched castor oil.

The appearance of the medicine is a white or yellowish matte substance.

The classic form of the drug contains:

• white refined wax;
• liquid form of paraffin;
• petrolatum;
• filtered water;
• emulsifier E.

The product is packaged in metal tubes with a capacity of 15 to 50 ml, which are placed in cardboard boxes.

what helps, hormonal or not

Advantan is an antiallergic, antibacterial, non-halogenated, opaque cream for external use, yellowish or white in color.
It is used in the treatment of various types of dermatoses. The use of the drug relieves allergic manifestations on the skin, restoring the integrity of the skin in children and adults. Based on the condition of the patient’s skin, the appropriate form of release of the drug is determined. The content of the article

Composition and release form

Today, manufacturers produce Advantan ointment in two forms: a classic cream on a water-emulsion basis and an option for external use on a fatty basis. Both types of the drug contain the same concentration of the hormone 0.1%, which forms a metabolite, penetrating into the dermis. Therefore, to the questions of many mothers about whether Advantan is hormonal or not, we can safely say that it is hormonal!

Please note that special Advantan cream for children is not available! Produced in tubes of 5,10,15 20, 25, 30 and 50 grams. Aluminum tubes are packaged in cardboard boxes, inside of which there are instructions with recommendations for the use of the drug. In addition to glucocorticoid hormone, the topical drug contains other excipients:

• white wax:
• liquid paraffin:
• emulsifier E;
• white Vaseline;
• purified water.

Composition of fatty ointment:

• soft paraffin;
• liquid paraffin;
• microcrystalline wax;
• hydrogenated castor oil.

How does Advantan ointment work?

Advantan ointment is able to easily penetrate cells, causing constriction of blood vessels and taking an active part in the synthesis of amino acids. This effect of the drug on the body leads to a decrease in itching, redness and pain in the affected areas.

The classic version of Advantan cream contains the correct ratio of fat and water. This option is used during the subsidence of inflammatory processes or for mild dermatitis. The pharmacological effect of the ointment, which is produced on a water-emulsion basis, is to eliminate inflammatory processes, dryness and restore the fatty film of the skin. The fatty version of Advantan ointment contains a high concentration of fatty acids, without water, which is why the drug is prescribed for the treatment of chronic, long-term diseases. The drug is produced exclusively from solid and liquid fats, which ensures that very dry skin retains moisture and prevents its removal. Advantan rich cream applied to the lesion creates a protective film for a long time, thus providing a strong therapeutic effect. The intensity of treatment depends on the condition of the patient’s skin, the method of use of the drug and its dosage form. For those who doubt whether to use Advantan ointment or cream, we hasten to answer that the choice of drug depends on the symptoms of the disease and skin type.

For what diseases should it be used?

Advantan ointment is prescribed for use for various types of eczema (occupational or microbial), dermatitis (atopic, contact or allergic), and for various types of rashes or swelling on the skin. For both forms of ointment, the indications for use are absolutely the same:

• diaper dermatitis;
• treatment of pityriasis rosea;
• photodermatitis, sunburn;
• dyshidrotic and childhood eczema.

Dosage regimen and method of administration

According to the instructions, you should use the ointment no more than once a day, applying a thin layer of it to the affected area of ​​the skin and allowing it to be absorbed. The drug should not be rubbed in.

The course of treatment, acceptable dosage and release form are prescribed by the doctor, individually for each patient. According to the instructions, the full course of treatment can be about 3 months for adults and 4 weeks for children. Water-emulsion cream, for sunburn, it is recommended to apply to the affected areas of the skin 2 times a day. If the skin is very dry, it is best to use the oily form of the drug.

Contraindications

The use of the hormonal drug Advantan is not recommended for certain diseases: skin tuberculosis, chickenpox, herpes zoster, skin manifestations of syphilis, rosacea, perioral dermatitis.

Do not use the product if your skin has a reaction after vaccination or is sensitive to glucocorticoid hormone.

Please note that Advantan for children, like the use of any other hormonal drug, is prohibited for children under 4 months of age. After the child has reached this age, the use of Advantan cream for children is permissible only on the recommendation of the attending pediatrician.

Nursing mothers should not apply Advantan to the mammary glands to prevent particles from entering the baby's body.

Use during pregnancy

Pregnant women are wary of all medications, which is why they often ask the question: “Is Advantan ointment hormonal or not? ”, because the use of any hormonal drug during pregnancy should be carried out on the recommendation and under the supervision of the attending physician. And Advantan ointment is no exception. It has been established that short-term use of the drug during pregnancy will not cause any harm to the mother and fetus.

Side effects

Advantan ointment is generally well tolerated unless overdose is observed. With prolonged use of the drug, the following adverse reactions may occur on the affected areas: rash formation, itching, skin atrophy, burning sensation, folliculitis, allergic reactions to the constituent components.

Sometimes allergic reactions to the skin may occur

Analogs

• Sinaflan. An inexpensive analogue that is effective for neurodermatitis, dermatitis, insect bites, seborrhea, psoriasis or eczema.
• Apulein. An effective substitute for Advantan ointment, which is prescribed for psoriasis, eczema, and atomic dermatitis. It has proven itself well in long-term treatment and does not have a resorptive effect.
• Locaselen. The combined agent has antiallergic, anti-inflammatory and anti-edematous effects. Used for: chronic dyshidrosis, lichen planus, lupus erythematosus, neurodermatitis.

Studying the interest of buyers in Advantan, we came to the conclusion that many buyers are interested in the question: “Is Advantan hormonal or not? “It is hormonal, experts answer, but the concentration of the hormone is very low, 0.1%.

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Treatment principle

The main active ingredient of both types of medicine is an artificial form of the hormone methylprednisolone aceponate, the content of which in the drug is no more than 0.1%. When the substance is applied to the affected area, active absorption of the ointment by the skin surface is observed.

Once in the middle layers of the epidermis, the hormone comes into contact with receptors that are sensitive to it. As a result, fewer white blood cells reach the inflamed area. The swelling of the tissue decreases, the redness disappears, and the affected area stops itching.

Treatment waste is eliminated by the kidneys after 16 hours. The product does not accumulate in the body.

It is allowed to use the ointment, applying it to 40-60% of the skin for 12 weeks in adult patients and 4 weeks in children. After special studies, no deviations in the composition of cortisol in human plasma were found; all hormonal indicators in the body correspond to the norm.

Advantan substitutes with similar medicinal properties

Substitutes with the active ingredient fluocinolone acetonide:

• ALERGODERM. Available in the form of an ointment (in tubes of 15 grams) containing 0.25 mg of active substance per 1 gram of the drug. Ukraine. It is used short-term – up to two weeks.
• FLUTS-DARNITSA. , Ukraine. The cream contains 1 mg of fluocinolone for each gram of the drug.
• FLUCIDERM. Country of origin: India, Jenom Biotech PVT. LTD. 0.25% cream is packaged in 15 gram tubes.
• FLUCINAR. Manufacturers: Jelfa SA, (Poland), VALEANT (Russia). Release form – gel, ointment, packaged in 15 g. into tubes.

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Advantan substitutes based on betamethasone GCS:

• BELODERM - 0.05% ointment and 0.1% cream, packaged in tubes of 15 and 30 g, manufacturer Belupo, Croatia. In accordance with the instructions, a 0.05% spray can be used to treat dermatoses.
• BETAMETHASONE. Dosage form - cream 0.64 mg/g, 15 g, manufacturer Kievmedpreparat, Ukraine.
• BETAZON. Available in the form of 0.1% cream, 15 and 30 grams in tubes. Produced by Health, Ukraine.
• BETLIBEN. Produced in Croatia by JSC Jadran. Release form – 0.05% ointment and cream, the drug is packaged in 25 gram tubes.
• MESODERM. Manufacturer: Borshchagovsky Chemical Plant, Ukraine. 0.1% cream is sold in tubes of 15 and 30 grams.
• SODERM. The drug is produced in Germany by the company Dermapharm. Available in the form of 0.1% ointment, cream, solution and emulsion.

Advantan substitutes based on fluticasone corticosteroids:

• KUTIVATE. 0.005% ointment and 0.05% cream are produced by the Polish company GlaxoSmithKline Pharmac. Packaged in tubes of 15 grams.
• FLUDERM. Dosage forms – cream (0.05 mg/g) and ointment (0.005 mg/g). Manufacturer: Ukrainian company Health.

Substitutes based on GCS mometasone:

• MOLESKIN. Produced (Ukraine). Available in the form of 0.1% ointment and cream.
• MOMAT. Produced in India by Glenmark Pharmaceuticals Ltd. Dosage forms - ointment and cream (0.1%), packaged in tubes of 5 and 15 grams.
• MOMEDERM. Produced in Poland by Elfa. Release form: cream, one gram of the drug contains 1 mg of mometasone.
• MOMESON. Manufacturer – joint Spanish-Ukrainian company Laboratory Reig Jofre, S.A. 0.1% cream is available in tubes of 30 and 60 grams.
• MOMEKON. Bilim Pharmaceuticals A.S., Türkiye. Dosage forms – 0.1% ointment, 0.1% cream, 0.1% lotion. The cream is sold in tubes of 15 and 30 g, ointment in 15 g. The lotion is packaged in 30 ml bottles.
• MOMETASONE. Produced by Farmak, Ukraine. 0.1% cream and ointment are packaged in tubes of 15 g.
• ELODERM. , Ukraine. 0.1% ointment is sold in tubes of 15 and 30 g.
• ELOSON. Manufactured by Pharma International, Jordan. 0.1% cream is sold in tubes of 30 g.

Advantan substitutes based on prednicarbate:

This group includes one medication – Prednitop. There are several dosage forms:

1. Oily and regular 0.25% ointment;
2. 0.25% cream, 10, 50, 30 grams in a tube;
3. 0.25% solution for the treatment of dermatological diseases of the scalp (50 and 100 ml in a bottle).

When is the drug most effective?

External use of both forms of the product helps restore skin health. The most effective treatment is in combination with medications prescribed by the treating dermatologist.

Indications for treatment:

• various types of eczema in children and adults (occupational, childhood, true, dyshidrotic, microbial);
• pityriasis rosea in children and adults;
• dermatitis of various etiologies (simple contact, allergic, atopic);
• neurodermatitis.

It is advisable for people with sensitive skin to conduct a preliminary test for the body’s reaction (apply a small amount of the substance to the crook of the elbow for 20 minutes). If there is no abnormal reaction, you can be treated with Advantan.

Description of the drug

Advantan ointment is a medical drug intended for external use. This remedy actively helps in eliminating the symptoms of allergic reactions, while simultaneously providing anti-inflammatory and anti-allergic effects on the skin.

Advantan is a non-halogenated steroid of synthetic origin that suppresses the inflammatory process and prevents the appearance of external symptoms that occur on the skin as a result of an allergic reaction.

Today, this remedy is considered one of the most effective and quite popular drugs.

This demand is explained by the fact that the ointment helps in different situations, relieving problems in the shortest possible time. However, not every buyer first studies the principle of action of the drug and the information contained in the instructions for use. But before using any medical product, it is better to familiarize yourself with it in advance.

Existing contraindications

Hormonal medicine is not recommended for use in some cases. These include:

• weeping wounds and ulcers in the area where the drug was applied;
• signs of a viral disease on the skin (chicken pox, lichen);
• manifestation of tuberculosis or syphilis on the skin;
• a pronounced reaction of the body to the vaccine;
• individual intolerance to the components of the drug;
• sores on the face near the mouth, eyes.

Advantan should not be used to treat infants under four months of age. In the case of pregnancy or breastfeeding a baby, it is necessary to compare the benefits of treatment with the harm that is caused to the body of the child and the mother. It is up to the attending physician to decide whether or not to use the medicine.

Nursing mothers should avoid applying the ointment to the breast.

Overdose and side effects of medication

If the recommended periods of use of the ointment are violated, some symptoms are observed. Among them:

• inflammatory process in hair follicles;
• pustular rash on the body;
• stretch marks;
• the appearance of pigment spots.

If you apply the medicine in a thick layer, burning and itching of the skin may occur. In this case, thinning and dying of the skin is observed. It is recommended to stop taking the ointment.

If a child has extensive skin lesions, applying ointment to the entire area is not recommended, as side effects may occur.

If the dosage and timing of treatment are observed, side effects occur in 1 person out of 10,000 patients, which is considered a fairly small value.

Characteristics of Advantan

This is a glucocorticosteroid drug intended to eliminate signs of skin diseases. It is used topically: it is applied to the affected tissue, the dosage is strictly regulated, since uncontrolled use of drugs from the GCS group leads to the development of complications. The active substance is methylprednisolone aceponate. Advantan is available in the form of cream and ointment, emulsion and fatty ointment.

The main properties of the drug:

Advantan is used as an antiproliferative agent. Thanks to this, the intensity of symptoms of conditions such as weeping, eczema, and swelling is reduced. Cells in areas where a negative process develops stop actively dividing. The tissue does not increase in size. As a result, the patient's condition is alleviated.

At the same time, itching is eliminated, the intensity of painful sensations is reduced, and irritation goes away.

Considering that Advantan is available in the form of cream, ointment and emulsion, it can be used externally, but the systemic effect in this case is not manifested, since the active component is not absorbed strongly enough into the tissue.

The mechanism of action of the active component is based on the ability to bind to intracellular glucocorticoid receptors. Another direction is the influence of the steroid-receptor complex on certain sections of DNA. There is an increase in the intensity of macrocortin production, which, in turn, affects the process of arachidonic acid release - inhibits it.

At the same time, the rate of production of prostaglandins and leukotrienes decreases. These are mediators of the inflammatory process. This means that soon the speed of its development will decrease. The drug provokes an increase in the vasoconstrictor activity of adrenaline. Advantan is prescribed for various inflammatory processes:

• eczema of various origins: true, dyshidrotic, microbial, occupational, neurodermatitis;
• dermatitis, including allergic ones.

Detailed instructions for treatment with hormonal ointment

It is recommended to lubricate the affected areas once a day. In this case, the ointment should be applied in a thin layer, without smearing or rubbing the composition into the skin. It is recommended to wait until the product is absorbed into the epidermis. Remains of the medicine must be carefully removed with a napkin.

Classic ointment is used to lubricate normal skin, and oily ointment is used for painfully dry, flaky skin. The maximum course of treatment is 3 months. The medicine does not affect the cause of the disease, but only removes unpleasant symptoms.

Prescription for children

Hormonal ointment is prescribed to children only in severe cases of allergies or skin inflammation. The medicine can be used externally from 4 months of age. It is recommended to adhere to the following rules:

• use the ointment for no more than 4 weeks, lubricating the skin with a thin layer once a day;
• In order for the drug to imitate the biological rhythm of the adrenal cortex as much as possible, it is recommended to lubricate the affected areas in the morning, adhering to the same time value;
• when prescribing treatment with hormones, the doctor must take into account the size of the affected skin surface, the age of the baby, clinical indicators of pathology, and the results of preliminary treatment;
• It is recommended to combine the use of Advantan ointment with other drugs so that the treatment shows maximum effect.

To reduce the concentration of the hormonal agent, pediatricians advise diluting the contents of the ointment with baby cream or olive oil, purified petroleum jelly in the following proportions:

• for infants up to one year – 1:10;
• up to three years of age – 1:7;
• up to 5 years – 1:4;
• up to 8-10 years – 1:3;
• 10-12 years old – 1:1.

Older children do not need to dilute the ointment. It is recommended to discontinue the medicine gradually.

Doctors' opinions

Reviews from experts about the drug:

I believe that for various clinical forms of atopic dermatitis, treatment with Advantan hormonal ointment is most suitable. The medicine is suitable for children over 1 year of age and adult patients because it has a quick effect. The likelihood of a side effect is extremely low. Of course, the disadvantage of the drug is its rather high price. On the other hand, treatment with cheaper drugs will take longer, which is comparable in cost to using Advantan.

Dermatologist A. Chuprin, 37 years old, Moscow

Advantan ointment acts gently, but quickly and effectively on areas of the child’s delicate skin affected by non-infectious inflammatory dermatosis (face, between the folds, bends of the limbs, armpits). I believe that with the correct dosage and treatment regimen, there is no danger of side effects. For unsure parents, an additional allergy test can be recommended. The medicine, of course, is a little expensive, but you shouldn’t skimp on children.

Pediatrician N. Ermolaev, 42 years old, Rostov-on-Don

Cream, ointment "Advantan": what helps

Indications for the use of Advantan include inflammatory skin diseases that are sensitive to therapy with topical corticosteroids:

• simple contact dermatitis;
• allergic (contact) dermatitis;
• atopic dermatitis, neurodermatitis, childhood eczema;
• true eczema;
• occupational eczema;
• dyshidrotic eczema;
• microbial eczema.

Why is Advantan emulsion prescribed? This form of medication is used if the patient has inflammatory skin diseases that are sensitive to therapy with topical corticosteroids:

• simple contact dermatitis;
• photodermatitis, sunburn;
• seborrheic dermatitis or eczema;
• microbial eczema;
• allergic (contact) dermatitis;
• atopic dermatitis, neurodermatitis, childhood eczema;
• true eczema.

Patient opinions

Patient reviews about the drug:

My son is six months old. The doctor diagnosed diaper dermatitis. Almost all types of diapers cause redness and itching of the buttocks. I'm just tired. Without diapers - constant washing, and with diapers - crying and restlessness of the baby. The doctor recommended the hormonal drug Advantan. The price is just crazy. But I bought something that you wouldn’t do for your child. Now my Alyoshka smiles, began to sleep peacefully, and I get enough sleep while it’s calm. I'm very pleased with the effect. Almost on day 2-3 all symptoms disappeared. Expensive, but the result is obvious!

Alena Bagatikova, 22 years old, Yaroslavl

Analogs

The cost of Advantan ointment analogues starts from 100 rubles, which is significantly cheaper than the original product. The following medications have similar properties:

1. Metizolone is effective for dermatitis, eczema, and dermatoses of the scalp, which are accompanied by severe itching. Contraindications are the same as for Advantan.
2. Sinaflan liniment is used for eczema, dermatitis, psoriasis of non-microbial origin. The active ingredient is fluocinolone acetonide. The drug is recommended for use in short courses on small affected areas. If the cause of the allergy is microbial, treatment should be combined with infectious therapy.
3. Fluciderm effectively eliminates allergic manifestations of the dry form of psoriasis, seborrheic dermatitis, and lichen planus. Restriction for children under two years of age. Treatment is recommended for no longer than 15 days, applying the product once a day.
4. Flucinar gel treats non-infectious allergic diseases that are accompanied by severe itching. Contraindicated in children under 2 years of age. The medicine should not be used for external manifestations of syphilis, chicken pox, or diaper dermatitis.

If a hormonal treatment is prescribed by a doctor, then this is the best option for the current disease. You must trust the experience and qualifications of doctors and not be afraid to take prescribed hormonal medications. It is recommended to strictly adhere to the dosage and treatment regimen.